Questions marked
with * are more appropriate
for residents.
4. The pathology illustrated below is a developmental malformation occurring in the second trimester
5. Complications of germinal matrix hemorrhage occurring at 22 weeks of gestation include all of
the following except:
*6. A baby boy was born at 29 weeks of gestation and was discharged from the NICU at 34 weeks. At 7 months
of age, spasticity of the lower extremities is apparent. The CT scan is shown below. The most
likely cause of the abnormality is:


*7. A 39 week pregnant woman detected decreased fetal movement. Biophysical profile was poor and the baby
was delivered by Cesarean section with Apgar scores of 1 and 3 at 1 and 5 minutes. The baby was
hypotonic, had poor respiratory effort, and died at 4 four days of gestation. Pathological examination
revealed HIE. Which of the following would be least severely affected?
8. The white matter is most frequently affected by HIE in:
9. This baby was born at 36 weeks of gestation and developed E. Coli sepsis and meningitis. He died
two weeks later. The changes in the brain shown below are due
to:

to:

10. This child was born at term and had spasticity and psychomotor retardation. He lived in an institution
for retarded children and died at 12 years of age. The brain
lesion shown below is due to:
lesion shown below is due to:
11. This baby was born at term. He was hypotonic, had a large transilluminating head, and died at
2 days of age. The brain at autopsy is shown below. Which of the following
statements about the brain pathology is not true:


12. This infant was born at 30 weeks of gestation and died three weeks later. The
brain lesions shown below represent:
brain lesions shown below represent:
13. This baby was born at 28 weeks of gestation. At 24 hours, he became hypotonic and his hematocrit
dropped to 23. He died three days later. The pathology illustrated below is due to:








