M2 NEUROPATHOLOGY COURSE

INTRODUCTION

The M2 NEUROPATHOLOGY course contains lectures (podcasts) and labs that can be offered as part of medical school M2 Systemic Pathology curriculum and integrated with Clinical Medicine content. The material on the website evolved from a course that has been offered at NEOMED since the early 80s. There are 9 lecture podcasts, covering cerebral ischemia and stroke, perinatal disorders, CNS infections, demyelinative diseases, brain tumors, neurodegenerative diseases, metabolic disorders, peripheral neuropathy, and myopathology. The course contains also 15 quizzes (matching multiple choice questions) in which students are asked to match gross and microscopic pathology images to clinical vignettes.

It would help if, before starting course, you refresh your memory on the following:
1. Basic gross anatomy: the meninges; the lobes of the brain, gross cortical landmarks (the motor and visual cortex, hippocampus, the Sylvian fissure); the visual pathway; the ventricles of the brain and their openings; the basal ganglia and thalamus; the brainstem (midbrain, pons, medulla, aqueduct, cerebral peduncles, substantia nigra, main brainstem nuclei, cranial nerves); the cerebellum; the main cerebral arteries and their territories.

2. Basic histology and reactions, e.g., axons, myelin, gliosis, microglial nodule, macrophages, what "degeneration" means. You will find these in Chapter 1"Neurocytology and basic reactions”. Some of these concepts are also explained at the beginning of each chapter.
Study each topic once well before the lecture, using the web site “http://neuropathology-web.org”. The lectures will not be a repetition of the web site material and will not dwell on details. It will be assumed that you have read the material and you are familiar with it in a general way. The lectures will then focus on basic principles of pathology and how they relate to clinical practice.

The labs are exercises that will further solidify your knowledge of basic principles and help you prepare for the exam. See Labs for further instructions.

If you follow the above plan, you will not need much further study. You will save yourselves time, and breeze through the course and the exam without anxiety. More important, you will have learned basic clinical neuropathology.


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